中科院院士、神经生物学家李朝义

简介

李朝义，男，中国科学院院士，  李朝义 院士中国著名神经科学家，现任中国科学院上海生命科学研究院神经科学研究所学术委员会主任、高级研究员，视觉与认知实验室研究组长，国际脑研究组织(IBRO)亚太地区委员会理事，复旦大学、中国科技大学、华中科技大学、电子科技大学、暨南大学和第三军医大学兼职教授和荣誉教授。

人物生平

1934年出生于重庆。1956年中国医科大学毕业。1961年复旦大学研究生毕业。现任中国科学院上海生命科学研究院生命中心研究员。1999年当选为中国科学院院士和国际脑研究组织（IBRO）亚太地区委员会理事。

先后在德国马克斯－普朗克生物物理化学研究所、美国普林斯顿大学、比利时  鲁文基督大学、加拿大麦基尔大学、日本九州工学院、和法国国家科学研究中心任客座科学家。受聘为复旦大学、中国科技大学、华中科技大学、暨南大学和第三军医大学兼职教授和荣誉教授。曾担任国家基金委神经科学、心理学、病理生理学、和医学评审组组长，和中国科学院重大交叉前沿研究项目“脑和意识研究”首席科学家。现兼任“中国神经科学杂志”主编。

荣誉贡献

主要从事视觉中枢研究，在国际刊物上发表了四十余篇研究论文（见publication list）。这些论文揭示了在视网膜、外膝体和视皮层各级神经元的感受野外面，都存在着一个范围比感受野大几十倍的“ 整合野”，系统地阐明了整合野在复杂图像信息处理中的重要性。在此基础上提出了感受野“ 三重结构”的新理论。这些结果已被国外广泛引用，并被国外学者应用于解释人类脑电图对图形刺激的反应，以及应用于神经网络和人工智能等研究领域。在视觉信息大范围整合研究方面处于国际前沿，该领域目前已成为国际上研究复杂视觉信息处理神经机制的热点。由于以上贡献，先后获得中国科学院自然科学二等奖（1991年）、国家自然科学二等奖（1997年）、和何梁何利科学与技术进步奖（2000年）。

个人作品

1. Zeng C, Li Y, Li C.Center-surroundinteraction with adaptiveinhibition: a computationalmodel for contourdetection.Neuroimage. 2011 Mar 1;55(1):49-66. Epub 2010 Nov 29.

2. Yao JG, Gao X, Yan HM, Li CY.,Field of attention for instantaneous object recognition.PLoS One. 2011 Jan 21;6(1):e16343. Free PMC Article PMID: 21283690 Free full text Related citations

3. Song XM, Wang Y, Zhu Z, Li CY.,Morphological bases of suppressive and facilitative spatial summation in the striate cortex of the cat.PLoS One. 2010 Nov 29;5(11):e15025.PMID: 21151335 Free PMC Article Free full text Related citations

4. Shen ZM, Xu WF, Li CY.,Cue-invariant detection of centre-surround discontinuity by V1 neurons in awake macaque monkey.J Physiol. 2007 Sep 1;583(Pt 2):581-92. Epub 2007 Jun 28.PMID: 17599965 Free PMC Article Free full text Related citations

5. Song XM, Li CY.,Contrast-dependent and contrast-independent spatial summation of primary visual cortical neurons of the cat.Cereb Cortex. 2008 Feb;18(2):331-6. Epub 2007 May 10. PMID: 17494058 Free Article Related citations

6. Xu WF, Shen ZM, Li CY.,Spatial phase sensitivity of V1 neurons in alert monkey.Cereb Cortex. 2005 Nov;15(11):1697-702. Epub 2005 Feb 9.PMID: 15703250 Free Article Related citations

7. Chen G, Dan Y, Li CY., Stimulation of non-classical receptive field enhances orientation ivity in the cat.J Physiol. 2005 Apr 1;564(Pt 1):233-43. Epub 2005 Jan 27.PMID: 15677690 Free PMC Article Free full text Related citations

8. Liu GB, Zhang Y, Pettigrew JD, Xu WF, Li CY.,Spreading and synchronization of intrinsic signals in visual cortex of macaque monkey evoked by a localized visual stimulus.Brain Res. 2003 Sep 19;985(1):13-20.PMID: 12957364 [PubMed - indexed for MEDLINE] Related citations

9. Yao H, Li CY.,Clustered organization of neurons with similar extra-receptive field properties in the primary visual cortex.Neuron. 2002 Aug 1;35(3):547-53.PMID: 12165475 [PubMed - indexed for MEDLINE] Related citations

10. Zhu Z, Wang Y, Xu XZ, Li CY.,A simple and effective method for obtaining stable in vivo whole-cell recordings from visual cortical neurons.Cereb Cortex. 2002 Jun;12(6):585-9.PMID: 12003858 [PubMed - indexed for MEDLINE] Free Article Related citations

11. 10 Ding J, Xu XZ, Li CY. Dye coupling between visual cortical (area 17) neurones of adult rat--a study on brain slices.Sheng Li Xue Bao. 1998 Jun;50(3):241-8. Chinese. PMID: 11324562 [PubMed - indexed for MEDLINE] Related citations

12. Li CY, Lei JJ, Yao HS.Shift in speed ivity of visual cortical neurons: a neural basis of perceived motion contrast.Proc Natl Acad Sci U S A. 1999 Mar 30;96(7):4052-6.PMID: 10097161 [PubMed - indexed for MEDLINE] Free PMC ArticleFree full text Related citations

13. Guo K, Li CY.Influence of visual stimuli on eye-position related activities of neurons in primary visual cortex (V1) of awake monkeys.Sheng Li Xue Bao. 1997 Aug;49(4):400-6. Chinese. PMID: 9812871 [PubMed - indexed for MEDLINE] Related citations

14. Li CY, Guo K. Gaze-position-dependent activities of striate cortex (V1) neurones of awake macaque monkeys.Sheng Li Xue Bao. 1997 Jun;49(3):299-306. Chinese. PMID: 9812815 [PubMed - indexed for MEDLINE] Related citations

15. Guo K, Li CY. Eye position-dependent activation of neurones in striate cortex of macaque. Neuroreport. 1997 Apr 14;8(6):1405-9.PMID: 9172144 [PubMed - indexed for MEDLINE] Related citations

16. Li CY. Integration Fields Beyond the Classical Receptive Field: Organization and Functional Properties. News Physiol. Sci. 1996 Aug; 11:181-186.

17. Li CY, Guo K. Measurements of geometric illusions, illusory contours and stereo-depth at luminance and colour contrast.Vision Res. 1995 Jun;35(12):1713-20.PMID: 7660579 [PubMed - indexed for MEDLINE] Related citations

18. Li CY, Xu XZ, David T.A simple and comprehensive method for the construction, repair and recycling of single and double tungsten microelectrodes. J of Neuroscience Methods. . 1995 Aug; 57:217-220.

19. Li W, Li CY.Shape and extent of the integration field of cat's striate cortical neurones. Sheng Li Xue Bao. 1995 Apr;47(2):111-9. Chinese. PMID: 7652586 [PubMed - indexed for MEDLINE] Related citations

20. Li CY, Li W. Extensive integration field beyond the classical receptive field of cat's striate cortical neurons--classification and tuning properties.Vision Res. 1994 Sep;34(18):2337-55.PMID: 7975275 [PubMed - indexed for MEDLINE] Related citations

21. Yin ZQ, Li CY, Pei X, Vaegan, Fang QX. Development of pattern ERG and pattern VEP spatial resolution in kittens with unilateral esotropia.Invest Ophthalmol Vis Sci. 1994 Feb;35(2):626-34.PMID: 8113013 [PubMed - indexed for MEDLINE] Free Article Related citations

22. Guo K, Li CY. Effects of luminance contrast and color contrast between components of illusory figure on the illusion magnitude.Sheng Li Xue Bao. 1993 Dec;45(6):543-51. Chinese. PMID: 8146679 [PubMed - indexed for MEDLINE] Related citations

23. Li CY, Guo K. Quantitative studies on discrimination of simple geometric patterns and related visual illusions.Sheng Li Xue Bao. 1993 Oct;45(5):486-97. Chinese. PMID: 8146672 [PubMed - indexed for MEDLINE] Related citations

24. Li CY, Zhou YX, Pei X, Qiu FT, Tang CQ, Xu XZ. Extensive disinhibitory region beyond the classical receptive field of cat retinal ganglion cells.Vision Res. 1992 Feb;32(2):219-28.PMID: 1574837 [PubMed - indexed for MEDLINE] Related citations

25. Li CY, Pei X, Zhow YX, von Mitzlaff HC. Role of the extensive area outside the X-cell receptive field in brightness information transmission.Vision Res. 1991;31(9):1529-40.PMID: 1949622 [PubMed - indexed for MEDLINE] Related citations

26. Creutzfeldt OD, Crook JM, Kastner S, Li CY, Pei X. The neurophysiological correlates of colour and brightness contrast in lateral geniculate neurons. I. opulation analysis.Exp Brain Res. 1991;87(1):3-21.PMID: 1756832 [PubMed - indexed for MEDLINE] Related citations

27. Li CY, Tanaka M, Creutzfeldt OD. Attention and eye movement related activation of neurons in the dorsal prelunate gyrus (area DP).Brain Res. 1989 Sep 4;496(1-2):307-13.PMID: 2804639 [PubMed - indexed for MEDLINE] Related citations

28. Li CY, He ZJ. Effects of patterned backgrounds on responses of lateral geniculate neurons in cat.Exp Brain Res. 1987;67(1):16-26.PMID: 3622676 [PubMed - indexed for MEDLINE] Related citations

29. Li CY, Nothdurft HC. Some observations on dynamic properties of receptive field organization of complex cells in cat visual cortex.Sci Sin B. 1987 Jan;30(1):44-54.PMID: 3602981 [PubMed - indexed for MEDLINE] Related citations

30. Li CY. Advances in the central mechanisms of vision.Sheng Li Ke Xue Jin Zhan. 1987 Jan;18(1):15-21. Review. Chinese. No abstract available. PMID: 3299687 [PubMed - indexed for MEDLINE] Related citations

31. Nothdurft HC, Li CY. Texture discrimination: representation of orientation and luminance differences in cells of the cat striate cortex.Vision Res. 1985;25(1):99-113.PMID: 3984222 [PubMed - indexed for MEDLINE] Related citations

32. Li CY, Creutzfeldt O. The representation of contrast and other stimulus parameters by single neurons in area 17 of the cat.Pflugers Arch. 1984 Jul;401(3):304-14.PMID: 6473083 [PubMed - indexed for MEDLINE] Related citations

33. Nothdurft HC, Li CY. Representation of spatial details in textured patterns by cells of the cat striate cortex.Exp Brain Res. 1984;57(1):9-21.PMID: 6519234 [PubMed - indexed for MEDLINE] Related citations

34. Ke Chen, Xue-Mei Song and Chao-Yi Li. Contrast-Dependent Variations in the Excitatory Classical Receptive Field and Suppressive Nonclassical Receptive Field of Cat Primary Visual Cortex.Cereb Cortex. 2012 Feb;22(3) doi: 10.1093